BDBM50118516 CHEMBL3617053

SMILES O=C(Nc1ccc(cc1)S(=O)(=O)Nc1nccs1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=URSQNPPONHUJDL-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50118516   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118516(CHEMBL3617053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NaV1.7 channel expressed in HEK293 cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118516(CHEMBL3617053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NaV1.8 channel by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118516(CHEMBL3617053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NaV1.6 channel by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118516(CHEMBL3617053)
Affinity DataIC50: <20nMAssay Description:Inhibition of human TTX-sensitive NaV1.3 channel expressed in HEK293 cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118516(CHEMBL3617053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NaV1.4 channel by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118516(CHEMBL3617053)
Affinity DataIC50:  240nMAssay Description:Inhibition of human NaV1.2 channel by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118516(CHEMBL3617053)
Affinity DataIC50: <20nMAssay Description:Inhibition of human NaV1.1 channel by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118516(CHEMBL3617053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NaV1.5 channel expressed in HEK293 cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed