BDBM50118700 6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one::CHEMBL136806

SMILES CC1(C)OC(=O)Nc2ccc(cc12)-c1cccc(Cl)c1

InChI Key InChIKey=VMPIROWONHUKCP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118700   

TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118700(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118700(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  9.30nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118700(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed