BDBM50120374 CHEMBL3616701
SMILES COc1ccc(cc1-c1nn(C(C)c2ccc(cc2)C(=O)NCCC(O)=O)c2cc(ccc12)-c1ccc(C)cc1)C(F)(F)F
InChI Key InChIKey=XIZYTDLDJKWLOW-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50120374
Affinity DataIC50: 7.60nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity against human glucose dependent insulinotropic peptide receptor by cAMP accumulation assayMore data for this Ligand-Target Pair