BDBM50120374 CHEMBL3616701

SMILES COc1ccc(cc1-c1nn(C(C)c2ccc(cc2)C(=O)NCCC(O)=O)c2cc(ccc12)-c1ccc(C)cc1)C(F)(F)F

InChI Key InChIKey=XIZYTDLDJKWLOW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120374   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50120374(CHEMBL3616701)
Affinity DataIC50:  7.60nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50120374(CHEMBL3616701)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50120374(CHEMBL3616701)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity against human glucose dependent insulinotropic peptide receptor by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed