BDBM50121363 CHEMBL3622106::US9751881, Example 4
SMILES Cc1c2COC(=O)c2ccc1CCN1CCC2(CN(C(=O)C2)c2ccc(cn2)C#N)CC1
InChI Key InChIKey=XPZUKKPVOPWXJD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50121363
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 12nMAssay Description:Assay Protocol: The ROMK channel functional thallium flux assay was performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells were ...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 12nMAssay Description:Inhibition of human Kir1.1 expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair