BDBM50124147 CHEMBL3622826

SMILES NCCn1c(nc2cc(ccc12)C(N)=O)C1CCNCC1

InChI Key InChIKey=XMMZUEFCWDQOPI-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50124147   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of JAK1 (unknown origin) using 1 mM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  4.37E+5nMAssay Description:Inhibition of JAK2 (unknown origin) using 1 mM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  2.33E+5nMAssay Description:Inhibition of JAK3 (unknown origin) using 1 mM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  7.60E+5nMAssay Description:Inhibition of Tyk2 (unknown origin) using 1 mM of ATP and Tyr3 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  50nMAssay Description:Inhibition of JAK1 (unknown origin) using 87 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Mus musculus)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  50nMAssay Description:Inhibition of FLAG-tagged mouse JAK1 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of JAK3 (unknown origin) using 16 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of Tyk2 (unknown origin) using 25 uM of ATP and Tyr3 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of FLAG-tagged human TYK2 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of FLAG-tagged human JAK3 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of FLAG-tagged human JAK2 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50124147(CHEMBL3622826)
Affinity DataIC50:  3.15E+3nMAssay Description:Inhibition of JAK2 (unknown origin) using 35 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed