BDBM50124147 CHEMBL3622826
SMILES NCCn1c(nc2cc(ccc12)C(N)=O)C1CCNCC1
InChI Key InChIKey=XMMZUEFCWDQOPI-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50124147
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of JAK1 (unknown origin) using 1 mM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.37E+5nMAssay Description:Inhibition of JAK2 (unknown origin) using 1 mM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.33E+5nMAssay Description:Inhibition of JAK3 (unknown origin) using 1 mM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataIC50: 7.60E+5nMAssay Description:Inhibition of Tyk2 (unknown origin) using 1 mM of ATP and Tyr3 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of JAK1 (unknown origin) using 87 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of FLAG-tagged mouse JAK1 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of JAK3 (unknown origin) using 16 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Tyk2 (unknown origin) using 25 uM of ATP and Tyr3 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of FLAG-tagged human TYK2 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of FLAG-tagged human JAK3 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of FLAG-tagged human JAK2 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of JAK2 (unknown origin) using 35 uM of ATP and Tyr6 peptide by Z'-LYTE kinase assayMore data for this Ligand-Target Pair