BDBM50127652 1-(4-Methanesulfonyl-phenyl)-8-methyl-4,5-dihydro-3aH-naphtho[2,1-b]furan-2-one::CHEMBL289447

SMILES Cc1ccc2CCC3OC(=O)C(=C3c2c1)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=KCJMUDJRPFAATN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127652   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50127652(1-(4-Methanesulfonyl-phenyl)-8-methyl-4,5-dihydro-...)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro inhibitory activity of the compound against recombinant human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50127652(1-(4-Methanesulfonyl-phenyl)-8-methyl-4,5-dihydro-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50127652(1-(4-Methanesulfonyl-phenyl)-8-methyl-4,5-dihydro-...)
Affinity DataIC50:  665nMAssay Description:In vitro inhibitory activity of the compound against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed