BDBM50129077 Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-cyclopentanecarbonyl)-amino]-4-oxo-azetidin-2-yl ester::CHEMBL62453

SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C1(CCCC1)NC(=O)OCc1ccccc1

InChI Key InChIKey=FUOXCWBCJJDEKN-ZBFHGGJFSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50129077   

TargetCathepsin K(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129077(Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-c...)
Affinity DataKi:  160nMAssay Description:Inhibitory activity of the compound was measured against Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129077(Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-c...)
Affinity DataKi:  7.70E+3nMAssay Description:Inhibitory activity of the compound was measured against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129077(Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-c...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibitory activity of the compound was measured against Cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129077(Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-c...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibitory activity of the compound was measured against Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed