BDBM50135375 6-[(4'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-5-(4-trifluoromethoxy-phenyl)-1,2-dihydro-pyridine-3-carbonitrile::CHEMBL338695

SMILES Cn1cncc1C(OCc1c(cc(C#N)c(=O)n1C)-c1ccc(OC(F)(F)F)cc1)c1ccc(C#N)c(c1)-c1ccc(Cl)cc1

InChI Key InChIKey=AQTMMHDZTUQGJD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135375   

LigandPNGBDBM50135375(6-[(4'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-...)
Affinity DataIC50:  6.5nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50135375(6-[(4'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibitory activity of the compound against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50135375(6-[(4'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-...)
Affinity DataEC50: >100nMAssay Description:In vitro effective concentration of the compound against farnesyltransferase (FT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed