BDBM50140650 6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-(4-trifluoromethoxy-phenyl)-6H-pyrrolo[3,4-d]pyridazine::CHEMBL24611

SMILES CCOc1ccc(cc1)-n1c(C)c2c(C)nnc(-c3ccc(OC(F)(F)F)cc3)c2c1C

InChI Key InChIKey=ZGSPTBBLXWOPHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140650   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140650(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-(4-trifluoro...)
Affinity DataIC50: 1.73E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed