BDBM50144233 4-[(S)-(R)-8-Aza-bicyclo[3.2.1]oct-(3E)-ylidene-phenyl-methyl]-N,N-diethyl-benzamide::CHEMBL63477

SMILES CCN(CC)C(=O)c1ccc(cc1)C(=C1/C[C@@H]2CC[C@H](C1)N2)\c1ccccc1

InChI Key InChIKey=HFTDPNTWNMNISE-JEOYDALESA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144233   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50144233(4-[(S)-(R)-8-Aza-bicyclo[3.2.1]oct-(3E)-ylidene-ph...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50144233(4-[(S)-(R)-8-Aza-bicyclo[3.2.1]oct-(3E)-ylidene-ph...)
Affinity DataKi:  2.31E+3nMAssay Description:Binding affinity for mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50144233(4-[(S)-(R)-8-Aza-bicyclo[3.2.1]oct-(3E)-ylidene-ph...)
Affinity DataEC50:  53nMAssay Description:Effective concentration against stimulation of [35S]-GTP-gammaS, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed