BDBM50146265 3-(4-Fluoro-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol::CHEMBL93546

SMILES Oc1ccc2OC(C(Sc2c1)c1ccc(F)cc1)c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=PXQIHYPEOSFFBY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146265   

TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146265(3-(4-Fluoro-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)...)
Affinity DataIC50:  67nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146265(3-(4-Fluoro-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)...)
Affinity DataIC50:  1.56E+3nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146265(3-(4-Fluoro-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146265(3-(4-Fluoro-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)...)
Affinity DataIC50:  94nMAssay Description:Potency in cellular transactivation assay utilizing HEK-293 cells stably co-transfected with human estrogen receptor alpha and the alkaline phosphata...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed