BDBM50146300 Biphenyl-2-carboxylic acid [4-(2,2-dioxo-1,2,3,4,11,11a-hexahydro-5H-2lambda*6*-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide::CHEMBL96255

SMILES O=C(Nc1ccc(cc1)C(=O)N1CC2CS(=O)(=O)CCN2Cc2ccccc12)c1ccccc1-c1ccccc1

InChI Key InChIKey=HTQQJZUIIOPAEI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146300   

TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50146300(Biphenyl-2-carboxylic acid [4-(2,2-dioxo-1,2,3,4,1...)
Affinity DataKi:  40nMAssay Description:Inhibition of 1 nM AVP-induced cAMP accumulation in cells expressing human vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50146300(Biphenyl-2-carboxylic acid [4-(2,2-dioxo-1,2,3,4,1...)
Affinity DataKi:  65nMAssay Description:Inhibition of [3H]AVP binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50146300(Biphenyl-2-carboxylic acid [4-(2,2-dioxo-1,2,3,4,1...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of 1 nM AVP-induced calcium mobilisation in cells expressing human vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed