BDBM50148608 CHEMBL3770119

SMILES ONC(=O)c1csc(Cc2ccccc2)n1

InChI Key InChIKey=JUYPUKFIMJDYEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148608   

TargetHistone deacetylase 1(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148608(CHEMBL3770119)
Affinity DataIC50:  8.36E+4nMAssay Description:Inhibition of human HDAC1 using (Z-(Ac)Lys-AMC) as substrate after 90 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148608(CHEMBL3770119)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(eta-trifluoroacetyl)-AMC as substrate after 90 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148608(CHEMBL3770119)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of human HDAC6 using (Z-(Ac)Lys-AMC) as substrate after 90 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed