BDBM50150899 (E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-phenyl-pentyl)-cyclopentyl]-hept-5-enoic acid isopropyl ester::CHEMBL364375::LATANOPROST (PHXA41)::Latanoprost (Isopropyl Ester)

SMILES CC(C)OC(=O)CCC\C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCc1ccccc1

InChI Key InChIKey=GGXICVAJURFBLW-UHFFFAOYSA-N

Data  11 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50150899   

TargetProstaglandin F2-alpha receptor(Human)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataEC50:  34.4nMAssay Description:Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Bovine)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi:  92nMAssay Description:Binding affinity for Prostanoid FP receptor of bovine corpus luteumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi:  555nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Bovine)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi:  4.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi:  8.54E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetSolute carrier organic anion transporter family member 2A1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Bovine)
Alcon Laboratories

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50150899BDBM50150899(LATANOPROST (PHXA41) | CHEMBL364375 | Latanoprost ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed