BDBM50156092 9-Cyclopentyl-6-(2-{4-[2-(2-methoxy-ethylamino)-ethoxy]-benzyloxy}-phenylamino)-9H-purine-2-carbonitrile::CHEMBL361499
SMILES COCCNCCOc1ccc(COc2ccccc2Nc2nc(nc3n(cnc23)C2CCCC2)C#N)cc1
InChI Key InChIKey=MLAYQZHQPOWWIL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50156092
Affinity DataIC50: 71nMAssay Description:Inhibitory concentration against recombinant human cathepsin S by using Z-Leu-Leu-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against recombinant human cathepsin K by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against recombinant human cathepsin L by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair