BDBM50158917 6-Methyl-[2,3'']bipyridinyl::CHEMBL368048::US8609708, 67

SMILES Cc1cccc(n1)-c1cccnc1

InChI Key InChIKey=JGRRGVGXYDGQLG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158917   

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158917(CHEMBL368048 | US8609708, 67 | 6-Methyl-[2,3'']bip...)
Affinity DataKi:  9.80E+3nMAssay Description:Effect on coumarin 7-hydroxylation by human Cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158917(CHEMBL368048 | US8609708, 67 | 6-Methyl-[2,3'']bip...)
Affinity DataIC50: 5.89E+4nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent