BDBM50159578 CHEMBL3785321

SMILES Cc1ccoc1C(=O)Nc1ccc(N2Cc3c(cccc3Cl)C2=O)c(Cl)c1

InChI Key InChIKey=FVHRTMALRHTFIM-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50159578   

TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159578(CHEMBL3785321)
Affinity DataEC50:  211nMAssay Description:Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159578(CHEMBL3785321)
Affinity DataEC50:  211nMAssay Description:Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159578(CHEMBL3785321)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulatory activity at human mGlu4 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159578(CHEMBL3785321)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159578(CHEMBL3785321)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159578(CHEMBL3785321)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50159578(CHEMBL3785321)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP34A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed