BDBM50164518 CHEMBL3800394
SMILES COc1ccc(cc1NC(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO
InChI Key InChIKey=MRHRACKJKBOJEI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50164518
TargetHistone deacetylase 1(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 6.34E+3nMAssay Description:Inhibition of recombinant human HDAC1 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair