BDBM50167718 2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)ethanone::2-Benzenesulfonyl-1-(4-trifluoromethyl-phenyl)-ethanone::CHEMBL383146

SMILES FC(F)(F)c1ccc(cc1)C(=O)CS(=O)(=O)c1ccccc1

InChI Key InChIKey=PDXUGNITDTZZFN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50167718   

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50167718(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration against human 11-beta-hydroxysteroid dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50167718(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)
Affinity DataIC50:  190nMAssay Description:Inhibitory concentration against human 11-beta-hydroxysteroid dehydrogenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50167718(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)
Affinity DataIC50:  187nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50167718(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50167718(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed