BDBM50169702 CHEMBL3805279

SMILES Oc1ccc(CNc2[nH]nc(c2-c2ccc(O)cc2)-c2ccc(O)cc2)cc1

InChI Key InChIKey=YRRFETZFOOWFGO-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169702   

TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169702(CHEMBL3805279)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169702(CHEMBL3805279)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169702(CHEMBL3805279)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50169702(CHEMBL3805279)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using mephenytoin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed