BDBM50171234 CHEMBL365751::[2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine

SMILES CN(C)CCc1c(C)[nH]c2ccc(Cl)cc12

InChI Key InChIKey=KSYMELKKLOFABL-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50171234   

Target5-hydroxytryptamine receptor 6(RAT)
Universit£

Curated by ChEMBL
LigandPNGBDBM50171234(CHEMBL365751 | [2-(5-Chloro-2-methyl-1H-indol-3-yl...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H] lysergic acid diethylamide from rat 5-HT6 receptor transfected in HEK293 cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50171234(CHEMBL365751 | [2-(5-Chloro-2-methyl-1H-indol-3-yl...)
Affinity DataKi:  245nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50171234(CHEMBL365751 | [2-(5-Chloro-2-methyl-1H-indol-3-yl...)
Affinity DataKi:  290nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50171234(CHEMBL365751 | [2-(5-Chloro-2-methyl-1H-indol-3-yl...)
Affinity DataKi:  300nMAssay Description:Binding affinity to human recombinant alpha2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171234(CHEMBL365751 | [2-(5-Chloro-2-methyl-1H-indol-3-yl...)
Affinity DataIC50:  40nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171234(CHEMBL365751 | [2-(5-Chloro-2-methyl-1H-indol-3-yl...)
Affinity DataEC50:  45nMAssay Description:Agonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair