BDBM50174146 CHEMBL3809691

SMILES [H][C@]12CNC(=O)c3cc([nH]c13)-c1cccc3nc(C)c(N[C@H](C)\C=C/C2)nc13

InChI Key InChIKey=DDQXBYGNFGPJRL-CLZWFORCSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174146   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50174146(CHEMBL3809691)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50174146(CHEMBL3809691)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human full-length Pim1 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser-112 preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed