BDBM50177696 3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperidin-4-yl)phenol::CHEMBL203307

SMILES C[C@@H]1C[C@](C)([C@@H](C)CN1CCc1ccccc1)c1cccc(O)c1

InChI Key InChIKey=PQWVLTVOZZLFQY-NJNPRVFISA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177696   

TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50177696(3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperi...)
Affinity DataKi:  15nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50177696(3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperi...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50177696(3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperi...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50177696(3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperi...)
Affinity DataIC50:  50nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed