BDBM50178272 CHEMBL201192::N-(2-cyclopropoxy-5-(trifluoromethoxy)benzyl)-1-phenyl-6-(1H-tetrazol-5-yl)-8-aza-bicyclo[3.2.1]octan-2-amine

SMILES FC(F)(F)Oc1ccc(OC2CC2)c(CNC2CCC3NC2(CC3c2nnn[nH]2)c2ccccc2)c1

InChI Key InChIKey=QZHOKWHGBRFWKM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178272   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178272(CHEMBL201192 | N-(2-cyclopropoxy-5-(trifluorometho...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178272(CHEMBL201192 | N-(2-cyclopropoxy-5-(trifluorometho...)
Affinity DataIC50:  0.650nMAssay Description:Displacement of [125I]-labelled substance P from cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed