BDBM50178666 CHEMBL196806::acetic acid 2-[[(3R,4R)-4-(4-chlorophenyl)-1-methyl-piperidin-3-yl]methylsufanyl]ethyl ester

SMILES CN1CC[C@H]([C@@H](CSCCOC(C)=O)C1)c1ccc(Cl)cc1

InChI Key InChIKey=NGCOVFQZQYNLNZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178666   

TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178666(acetic acid 2-[[(3R,4R)-4-(4-chlorophenyl)-1-methy...)
Affinity DataKi:  125nMAssay Description:Ability to inhibit [3H]5-HT uptake through SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178666(acetic acid 2-[[(3R,4R)-4-(4-chlorophenyl)-1-methy...)
Affinity DataKi:  177nMAssay Description:Ability to inhibit [3H]DA uptake through DAT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178666(acetic acid 2-[[(3R,4R)-4-(4-chlorophenyl)-1-methy...)
Affinity DataKi:  610nMAssay Description:Ability to inhibit [3H]NE uptake through NET in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed