BDBM50183391 CHEMBL3818563
SMILES CCOc1cc2ncnc(N[C@@H](C)c3ccccc3)c2cc1NC(=O)[C@@H]1COC(=O)N1
InChI Key InChIKey=KIKYDYDKITYLHU-UGSOOPFHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50183391
Affinity DataIC50: 5.5nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair