BDBM50188029 3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid::CHEMBL209749

SMILES CCOC(Cc1ccc2n(Cc3nc(oc3C)-c3ccccc3Cl)ccc2c1)C(O)=O

InChI Key InChIKey=PAWOPJKHTZCKMT-UHFFFAOYSA-N

Data  2 IC50  3 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188029   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataEC50:  810nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay relative to farglitazarMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataEC50:  760nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay relative to edaglitazoneMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataIC50:  251nMAssay Description:Binding affinity to PPARgamma by radio ligand binding assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataEC50:  4.60E+3nMAssay Description:Activity at PPARdelta by luciferase reporter gene transactivation assay relative to GW 501516More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataIC50:  73nMAssay Description:Binding affinity to PPARalpha by radio ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed