BDBM50188768 1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-(2-(trifluoromethyl)phenyl)urea::CHEMBL215417

SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(CNC(=O)Nc4ccccc4C(F)(F)F)s3)c2)CC1

InChI Key InChIKey=OLXWFZOBAFYNHM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188768   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188768(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of KDR at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188768(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of cKit at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188768(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FLT1 at 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed