BDBM50190335 4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfonamide::CHEMBL215872

SMILES NS(=O)(=O)c1ccc(cc1)N=Nc1ccc(O)c(Cl)c1

InChI Key InChIKey=CNOMOEITTQLGJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190335   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50:  3.97E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50:  4.05E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed