BDBM50192470 (3-chloro-2-fluoro-phenyl)-(7,8-dimethoxy-3-methyl-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-amine::CHEMBL386052

SMILES COc1cc2CNc3c(Nc4cccc(Cl)c4F)nc(C)nc3Oc2cc1OC

InChI Key InChIKey=MTSNGHVNGCZYBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192470   

TargetVascular endothelial growth factor receptor 2(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50192470((3-chloro-2-fluoro-phenyl)-(7,8-dimethoxy-3-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50192470((3-chloro-2-fluoro-phenyl)-(7,8-dimethoxy-3-methyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed