BDBM50193358 (E)-1-(4-chlorophenyl)-3-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)propan-1-one O-methyl-oxime::CHEMBL213097

SMILES CO\N=C(/CCN1CCC(CC1)c1cccc[n+]1[O-])c1ccc(Cl)cc1

InChI Key InChIKey=UXZSXFCPMYKUSL-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193358   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193358((E)-1-(4-chlorophenyl)-3-(1-oxy-3',4',5',6'-tetrah...)
Affinity DataEC50:  84nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193358((E)-1-(4-chlorophenyl)-3-(1-oxy-3',4',5',6'-tetrah...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193358((E)-1-(4-chlorophenyl)-3-(1-oxy-3',4',5',6'-tetrah...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed