BDBM50197666 CHEMBL3977401
SMILES CC1(CCS(=O)(=O)CC1)C1CN(CCOc2ccc(F)c(c2)C#N)C(=O)C1
InChI Key InChIKey=SYEMWCXBADSSGE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50197666
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate additionMore data for this Ligand-Target Pair