BDBM50202085 (R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}propionamide::(S)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}propionamide::CHEMBL425104

SMILES C[C@H](N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2

InChI Key InChIKey=RSIROJJHJFVYIR-BXNVBKHCSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50202085   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataKi:  4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataKi:  4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataKi:  5nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataKi:  5nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed