BDBM50203947 (2-methyl-benzyl)-(S)-pyrrolidin-3-yl-(tetrahydro-pyran-4-yl)-amine::CHEMBL397392
SMILES Cc1ccccc1CN([C@H]1CCNC1)C1CCOCC1
InChI Key InChIKey=WMWARSGGACJLII-KRWDZBQOSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50203947
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]NA from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of [3H]5HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair