BDBM50204769 8-(5-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL240005

SMILES Fc1cccc2C(CCCc12)N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key InChIKey=YTTZUCWHSUQLJS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204769   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204769(8-(5-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204769(8-(5-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204769(8-(5-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204769(8-(5-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed