BDBM50204834 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine::CHEMBL238125

SMILES Fc1ccc(Cl)cc1-c1nc(Nc2ccncc2)c2nccnc2n1

InChI Key InChIKey=BERLXWPRSBJFHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50204834   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204834(2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pterid...)
Affinity DataIC50:  53nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204834(2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pterid...)
Affinity DataIC50:  48nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204834(2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pterid...)
Affinity DataIC50:  35nMAssay Description:Inhibition of TGFBR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed