BDBM50206413 CHEMBL3974375

SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc2[nH]nc(-c3cccc(NC(=O)\C=C/C(O)=O)c3)c2c1

InChI Key InChIKey=VHRBAOFJRSFVHL-QXMHVHEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206413   

TargetAurora kinase B(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50206413(CHEMBL3974375)
Affinity DataIC50:  32nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50206413(CHEMBL3974375)
Affinity DataIC50:  310nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed