BDBM50209684 CHEMBL390718::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole

SMILES COc1cc2NCC3C(CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC

InChI Key InChIKey=JODRRUQCPGURFJ-CPNJWEJPSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50209684   

TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha2A receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha2A receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic Alpha-2C receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic Alpha-2C receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]paroxetine from human cloned 5HTT receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]paroxetine from human cloned 5HTT receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha-2B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed