BDBM50210258 CHEMBL3920872

SMILES OC(=O)CCCCCCOc1ccc2Nc3nccc(n3)-c3cccc(COC\C=C\COCc1c2)c3

InChI Key InChIKey=NPPBVGZMTQAIFX-AATRIKPKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210258   

TargetHistone deacetylase 6(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210258(CHEMBL3920872)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells preincubated with enzyme followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210258(CHEMBL3920872)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed