BDBM50211433 CHEMBL391794::N-ethyl-4-(4-(2-isopropyl-1H-indol-3-yl)pyrimidin-2-ylamino)piperidine-1-carboxamide

SMILES CCNC(=O)N1CCC(CC1)Nc1nccc(n1)-c1c([nH]c2ccccc12)C(C)C

InChI Key InChIKey=GLLVHHZWPVUNED-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211433   

TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211433BDBM50211433(N-ethyl-4-(4-(2-isopropyl-1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50: 520nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211433BDBM50211433(N-ethyl-4-(4-(2-isopropyl-1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50: 698nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211433BDBM50211433(N-ethyl-4-(4-(2-isopropyl-1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 by IMAP technologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211433BDBM50211433(N-ethyl-4-(4-(2-isopropyl-1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of cJun translocation in IL-1-beta-stimulated A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed