BDBM50214937 (Z)-5-(4-ethylbenzylidene)-10-methoxy-2,2,4-trimethyl-2,4a,5,12a-tetrahydro-1H-chromeno[3,4-f]quinolin-9-ol::CHEMBL232173
SMILES CCc1ccc(\C=C2/Oc3ccc(O)c(OC)c3C3=C2C2C(NC(C)(C)C=C2C)C=C3)cc1
InChI Key InChIKey=UKSXBIXGPZTRIP-IWIPYMOSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50214937
Affinity DataKi: 1.90nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 207nMAssay Description:Agonist activity at GR by GRE activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Antagonist activity at GR assessed as inhibition of dexamethasone-induced GRE activationMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Activity at GR assessed as repression of TNFalpha and IL 1beta induced E-selectin responseMore data for this Ligand-Target Pair