BDBM50215926 4-(4,5-dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine::Ageladine A::CHEMBL230806
SMILES Nc1nc2c(nccc2[nH]1)-c1cc(Br)c(Br)[nH]1
InChI Key InChIKey=QAKGJAQGTQLMFN-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50215926
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Beckman Research Institute At City Of Hope
Curated by ChEMBL
Beckman Research Institute At City Of Hope
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Beckman Research Institute At City Of Hope
Curated by ChEMBL
Beckman Research Institute At City Of Hope
Curated by ChEMBL
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Beckman Research Institute At City Of Hope
Curated by ChEMBL
Beckman Research Institute At City Of Hope
Curated by ChEMBL
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PIM1 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair