BDBM50218283 5-chloro-N-((3R,4S)-1-(ethylsulfonyl)-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)pyrrolidin-3-yl)thiophene-2-carboxamide::CHEMBL392297
SMILES CCS(=O)(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O
InChI Key InChIKey=YPEJQZNLCKSDCY-ZWKOTPCHSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50218283
Affinity DataKi: 0.640nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 3.95E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6.68E+3nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
Affinity DataKi: >1.08E+4nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
Affinity DataKi: >1.10E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: >1.40E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of human PlasminMore data for this Ligand-Target Pair