BDBM50220287 (2S)-9-(4-chlorophenylsulfonyl)-9-aza-bicyclo[3.3.1]nonan-2-yl 4-(piperidin-1-yl)piperidine-1-carboxylate::CHEMBL236193

SMILES Clc1ccc(cc1)S(=O)(=O)N1C2CCCC1[C@H](CC2)OC(=O)N1CCC(CC1)N1CCCCC1

InChI Key InChIKey=NAVFWCKQAIOHRB-HQNXYIODSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220287   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220287((2S)-9-(4-chlorophenylsulfonyl)-9-aza-bicyclo[3.3....)
Affinity DataIC50:  15nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed