BDBM50220287 (2S)-9-(4-chlorophenylsulfonyl)-9-aza-bicyclo[3.3.1]nonan-2-yl 4-(piperidin-1-yl)piperidine-1-carboxylate::CHEMBL236193
SMILES Clc1ccc(cc1)S(=O)(=O)N1C2CCCC1[C@H](CC2)OC(=O)N1CCC(CC1)N1CCCCC1
InChI Key InChIKey=NAVFWCKQAIOHRB-HQNXYIODSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50220287
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair