BDBM50220571 CHEMBL355250

SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1ccccn1

InChI Key InChIKey=KSMWRTSICDAGPU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220571   

TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220571(CHEMBL355250)
Affinity DataIC50:  4.20E+4nMAssay Description:In vitro inhibitory activity against Aspergillus fumigatus Nmt (AfNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220571(CHEMBL355250)
Affinity DataIC50:  3.40E+5nMAssay Description:In vitro inhibitory activity against human Nmt (HsNmt) using 0.5 uM peptide GNAASAR-R-NH2 and 0.5 uM myristoyl-CoAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50220571(CHEMBL355250)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed