BDBM50223187 CHEMBL30966

SMILES C(Nc1nc(CC2CCCC2)nc2ccsc12)c1ccccc1

InChI Key InChIKey=YCEREBUFXGBUFZ-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50223187   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50223187(CHEMBL30966)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against (PDE IV) phosphodiesterase IV in guinea pig articular tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223187(CHEMBL30966)
Affinity DataIC50:  5.80E+3nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50223187(CHEMBL30966)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50223187(CHEMBL30966)
Affinity DataEC50:  3.40E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223187(CHEMBL30966)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory activity against cGMP inhibited Phosphodiesterase 3, isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed