BDBM50224217 2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5H)-one::CHEMBL236174

SMILES CC(C)c1sc(Nc2cc(F)ccc2F)nc1O

InChI Key InChIKey=XZKMZCXJUBITPX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224217   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224217(2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataKi:  12nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224217(2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed