BDBM50227600 CHEMBL254837::but-2-ynyl 6-oxo-1,6-dihydropyridine-2-carboxylate

SMILES CC#CCOC(=O)c1cccc(=O)[nH]1

InChI Key InChIKey=IGTOOKSKMAGIMJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50227600   

TargetMacrophage metalloelastase(Homo sapiens (Human))
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227600(CHEMBL254837 | but-2-ynyl 6-oxo-1,6-dihydropyridin...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227600(CHEMBL254837 | but-2-ynyl 6-oxo-1,6-dihydropyridin...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227600(CHEMBL254837 | but-2-ynyl 6-oxo-1,6-dihydropyridin...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227600(CHEMBL254837 | but-2-ynyl 6-oxo-1,6-dihydropyridin...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed