BDBM50228426 CHEMBL391344::diphenyl 1-(naphthalenesulfonylamino)-2-(4-guanidinophenyl)-ethanephosphonate

SMILES [#7]\[#6](-[#7])=[#7]\c1ccc(-[#6]-[#6](-[#7]S(=O)(=O)c2cccc3ccccc23)P(=O)([#8]-c2ccccc2)[#8]-c2ccccc2)cc1

InChI Key InChIKey=GCGJCPGMBVJZFF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50228426   

TargetCoagulation factor X(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228426(CHEMBL391344 | diphenyl 1-(naphthalenesulfonylamin...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228426(CHEMBL391344 | diphenyl 1-(naphthalenesulfonylamin...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228426(CHEMBL391344 | diphenyl 1-(naphthalenesulfonylamin...)
Affinity DataIC50:  26.5nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228426(CHEMBL391344 | diphenyl 1-(naphthalenesulfonylamin...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228426(CHEMBL391344 | diphenyl 1-(naphthalenesulfonylamin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed