BDBM50233597 CHEMBL4091363

SMILES COc1cc(Br)c(C[C@H]2C[C@H]2C(O)=O)c(Br)c1OC

InChI Key InChIKey=JYYXECVMEBTPHQ-RNFRBKRXSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233597   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50233597(CHEMBL4091363)
Affinity DataKi:  0.540nMAssay Description:Inhibition of human CA1 using para-nitrophenylacetate as substrate measured over 3 mins by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50233597(CHEMBL4091363)
Affinity DataKi:  8.90nMAssay Description:Inhibition of human CA2 using para-nitrophenylacetate as substrate measured over 3 mins by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50233597(CHEMBL4091363)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50233597(CHEMBL4091363)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed